What's the best Pop-Up Blocker? Anti-Virus Software? Anti-Spyware Software?

One of the other things that had become veryclear, especially in the Anti-Virus arena and in the Anti-Spyware arena is that there is no clear winner. There is not one software package I can point you at - or for that matter use myself - that will catch everything.

We are fond of Microsoft's FREE DEFENDER product and Paretologic's Registry Cleaner and Anti-Spyware products.